Molecular BiologyNature CommunicationsPeer-reviewed
Deciphering the History of ERK Activity from Fixed-Cell Immunofluorescence Measurements
Abhineet R. Ram, Michael Pargett, Yongin Choi…·John G. Albeck
The paper develops a framework to infer ERK signaling dynamics from fixed-cell immunostains by combining machine learning and differential equations, showing that protein levels reflect different activation timescales.
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