Developmental BiologybioRxivPreprint
Genome-Wide Identification of HES1 Target Genes Uncover Novel Roles for HES1 in Pancreatic Development
Kristian Honnens de Lichtenberg, Nina Sofi Funa, Nikolina Nakić…·Palle Serup
The paper identifies HES1 target genes using ChIP-seq and RNA-seq in hESC lines, revealing HES1's role in pancreatic development through Notch pathway regulation and suppression of intestinal gene programs.