TGF-β modulates cell fate in human ES cell-derived foregut endoderm by inhibiting multiple endogenous signaling pathways
Nina Sofi Funa, Kristian Honnens de Lichtenberg, Maria Skjøtt Hansen, Jonas van Cuyl Kuylenstierna, Kim Bak Jensen, Yi Miao, K. Christopher García, Palle Serup
This study identifies how TGF-β1 modulates cell fate in human ES cell-derived foregut endoderm by inhibiting multiple signaling pathways, promoting pancreas fate over liver.
bioRxiv · Jul 15, 2021 · PreprintDevelopmental Biology