BiochemistryJournal of Biological ChemistryPeer-reviewed
Optical Control of Cell-Surface and Endomembrane-Exclusive β-Adrenergic Receptor Signaling
Waruna Thotamune, Sithurandi Ubeysinghe, Kendra K. Shrestha…·Ajith Karunarathne
This paper introduces OptoIso, a photo-labile ligand that selectively activates βAR signaling at the cell surface or endomembranes using blue light, enabling precise study of its role in cardiac pathology.