Fabio Sacher

Molecular address codes delineate circuit-specific motor neuron-muscle matchmaking in the developing tetrapod limb

The paper identifies molecular address codes in motor neurons and muscles that guide specific neuromuscular connections in tetrapod limbs through transcriptomic analysis and computational tools.

Transcriptional and cellular maturation of the chick spinal cord in the context of distinct neuromuscular circuits

The paper studies the transcriptional and cellular maturation of the chick spinal cord at single-cell resolution, revealing similar cell type repertoires for wings and legs and limited transcriptional changes with spatially restricted plasticity in motor neurons.

Extracellular matrix gene expression signatures as cell type and cell state identifiers

The paper shows that extracellular matrix gene expression can identify cell types and states better than random gene subsets and can match transcription factors in some cases.

A Single-cell Transcriptomic Atlas of the Developing Chicken Limb

The paper creates a single-cell RNA-seq atlas of the developing chicken limb, identifying 23 cell populations and uncovering molecular sub-populations and gene co-expression modules.