Oren Parnas

The paper identifies four epithelial transcription states in pancreatic cancer and links their origins to early developmental processes.

The paper identifies context-dependent factors affecting CRISPR-Cas9 editing efficiency across species using endogenous editing data and shows that repair outcomes are conserved.

The paper constructs a single-cell splicing atlas of human CD8 T cells and identifies isoform-specific immune checkpoints that enhance effector function and tumor control.

The paper creates a single-cell RNA-seq atlas of the developing chicken limb, identifying 23 cell populations and uncovering molecular sub-populations and gene co-expression modules.