Galectin-1 Modulates Hepatocellular Carcinoma Response to Thermal Ablation Through Regulating Glycolysis
Tu Anh Nguyen, Yonghwan Shin, Aravinth Ruppa, Abigail S. Krall, Janet Pham, Po-Chun Chen, Hannah Mirmohammadi, Pedram Keshavarz, Richard S. Finn, Vatche Garen Agopian, Samuel William French, Heather R. Christofk, David Lu, Steven S. Raman, Jason Chiang
This study identifies galectin-1 as a prognostic biomarker for predicting thermal ablation response in hepatocellular carcinoma and shows that targeting Gal-1 enhances ablation efficacy by modulating glycolysis.
Hepatology · May 21, 2025Peer-reviewedCancer Biology