ImmunologybioRxivPreprint
Engineering Endogenous T Cell Receptors to Recognize Cancer Neoantigens Using a Hybrid Physics-AI Approach
Jeffrey K. Weber, Gyanu Parajuli, S H Wang…·Timothy An-thy Chan
The paper uses a hybrid physics-AI approach to engineer functional TCRs targeting cancer neoantigens, showing improved efficacy compared to patient-derived TCRs.
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