Author

Christina Gaughan

Cleveland ClinicORCID 0000-0002-0869-9026Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Abhishek AsthanaiD· 1 shared Anders Henrik LundiD· 1 shared Claudia Marcela Diaz-MonteroiD· 1 shared Efrat HexteriD· 1 shared Frederic Schrøder ArendrupiD· 1 shared Goda SnieckuteiD· 1 shared Gyanu ParajuliiD· 1 shared Ivan JurićiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Abhishek AsthanaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 19, 2026

Engineering Endogenous T Cell Receptors to Recognize Cancer Neoantigens Using a Hybrid Physics-AI Approach

Jeffrey K. Weber, Gyanu Parajuli, S H Wang…·Timothy An-thy Chan

The paper uses a hybrid physics-AI approach to engineer functional TCRs targeting cancer neoantigens, showing improved efficacy compared to patient-derived TCRs.

1 citation

humanproteomics

𝕏 PostBluesky

ImmunologyCell ReportsPeer-reviewedMar 28, 2024

Initiation of a ZAKa-dependent Ribotoxic Stress Response by the Innate Immunity Endoribonuclease RNase L

Jiajia Xi, Goda Snieckute, José Francisco Martínez…·Robert H. Silverman

This study shows that RNase L activation by 2-5A triggers a ZAK-dependent ribotoxic stress response, leading to inflammatory gene transcription and apoptosis.

27 citations

humanbulk RNA-seq

𝕏 PostBluesky