Author

Keshav Gopal

University of AlbertaORCID 0000-0002-3320-2990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Abdualrahman Mohammed AbdualkaderiD· 1 shared Ahmed M. DarweshiD· 1 shared Amanda A. GreenwelliD· 1 shared Christina T. SaediD· 1 shared Farah EatoniD· 1 shared Gary D. LopaschukiD· 1 shared Golam Mezbah UddiniD· 1 shared John M. SeubertiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Abdualrahman Mohammed AbdualkaderORCID

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1 paper

Recent·Most cited

Cell BiologyJournal of Biological ChemistryPeer-reviewedOct 20, 2023

Loss of Skeletal Muscle Pyruvate Dehydrogenase Induces Lactic Acidosis and Adaptive Anaplerotic Compensation via Pyruvate-Alanine Cycling and Glutaminolysis

Keshav Gopal, Abdualrahman Mohammed Abdualkader, Xiaobei Li…·Rami Al Batran

This study shows that loss of skeletal muscle pyruvate dehydrogenase causes lactic acidosis and early death, but high-fat diets can mitigate these effects.

24 citations

mousemetabolomics

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