Author

Aleksandr M. Gorin

University of California, Los AngelesORCID 0000-0002-3330-4970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alexander HoffmanniD· 1 shared Noa C. HarriottiD· 1 shared Quen J. ChengiD· 1 shared Vyas KoduvayuriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

Alexander HoffmannORCID

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1 paper

Recent·Most cited

IFNγ-induced memory in human macrophages is not sustained by epigenetic changes but the durability of the cytokine itself

Aleksandr M. Gorin, Noa C. Harriott, Vyas Koduvayur, Quen J. Cheng, Alexander Hoffmann

This study shows that IFNγ-induced memory in macrophages relies on ongoing cytokine signaling, not epigenetic changes, as cytokine removal reverses enhancer formation and memory.

bioRxiv · Jun 12, 2025 · PreprintImmunology