Author

Sergio Sánchez‐García

Instituto de Salud Carlos IIIORCID 0000-0002-3332-7603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Adrián Povo‐RetanaiD· 1 shared Anirban ChakrabortyiD· 1 shared Balaji KrishnaniD· 1 shared Fred H. GageiD· 1 shared Gourisankar GhoshiD· 1 shared Jérôme MertensiD· 1 shared Johannes C. M. SchlachetzkiiD· 1 shared Joseph R. HerdyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Adrián Povo‐RetanaORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintMay 31, 2026

A Toxic Tau-PFKFB3 Circuit Reduces F2,6BP Levels and Drives Neurodegeneration

Santi M Mandal, Anirban Chakraborty, Shandy Shahabi…·Gourisankar Ghosh

This paper identifies the PFKFB3-F2,6BP metabolic axis as a key driver of Alzheimer's disease by linking metabolic dysregulation to genomic stability and Tau proteostasis, showing that F2,6BP supplementation rescues AD phenotypes across multiple models.

DOI 10.64898/2026.05.28.728580

humanDrosophila

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