Pharmacology & ToxicologybioRxivPreprint
Ruxolitinib clears CRYAB p.Arg120Gly aggregates through the ubiquitin-proteasome system
Erda Alizoti, Leonie Ewald, Simona Parretta…·Sonia R. Singh
This study shows ruxolitinib reduces CRYAB p.Arg120Gly protein aggregates in DRM models by enhancing the ubiquitin-proteasome system.