Functional Human Retinohypothalamic Tract Assembloid Model for Circadian Rhythm Research
Burak Kahveci, Ece Çakıroğlu, Hümeyra Nur Kaleli, Seden Nadire Harputoglu Efendi, Burak Derkuş, Omer Faruk Ozelci, Sedat Nizamoğlu, İbrahim Halil Kavaklı, Serif Senturk, Hayrünnisa Bolay, Bayram Yılmaz, Sinan Güven
This paper develops a functional human retinohypothalamic tract assembloid to study circadian rhythms, showing synchronized network activity and self-sustained gene expression oscillations.
bioRxiv · Jan 23, 2026 · PreprintBioengineering