This study examines long-term neurovascular dysfunction and altered placenta-derived EV miRNA profiles in a rat model with preeclamptic features, identifying miR-363-3p as a potential protective factor.

bioRxiv · Sep 22, 2025 · PreprintBioinformatics

Sex-Specific Cardiovascular Adaptations to Simulated Microgravity in Sprague-Dawley Rats

Ebrahim Elsangeedy, Dina N. Yamaleyeva, Nicholas P. Edenhoffer, Allyson Deak, Anna Soloshenko, Jonathan Ray, Xuming Sun, Omar H. Shaltout, Nildris Cruz‐Diaz, Brian M. Westwood, Daniel B. Kim‐Shapiro, Debra I. Diz, Shay Söker, Víctor M. Pulgar, April E. Ronca, , Liliya M. Yamaleyeva

This study examines sex-specific cardiovascular adaptations to simulated microgravity in rats, finding increased arterial stiffness in females but not males.

npj Microgravity · Dec 18, 2024Peer-reviewedPhysiology

Angiotensin Converting Enzyme Hub Model of Peptide Flux Relating Calculated AT1 Receptor and Aldosterone Levels

Brian M. Westwood, Mark C. Chappell

The paper develops a hub model of peptide flux in the RAAS system using VICTAS Trial data to relate AT1 receptor and aldosterone levels.

bioRxiv · Aug 20, 2024 · PreprintSystems Biology

Discrete Correlate Summation Clustering of a Dopamine-Angiotensin Network

Brian M. Westwood, Liliya M. Yamaleyeva, Rong Chen

The paper uses discrete correlate summation clustering to analyze a dopamine-angiotensin protein network defined by Swiss-Prot keywords.

bioRxiv · Jun 22, 2024 · PreprintBioinformatics