Ashish Kumar

This paper identifies myeloid Gi signaling as a weight-independent immunometabolic switch that regulates systemic insulin sensitivity through opposing cytokine programs.

This study shows that activating Gq-signaling in islet macrophages impairs β-cell insulin secretion via the AMPK-sphingolipid axis, revealing a new immune-endocrine communication mechanism.

This study examines long-term neurovascular dysfunction and altered placenta-derived EV miRNA profiles in a rat model with preeclamptic features, identifying miR-363-3p as a potential protective factor.

This study identifies miR-203a-3p as a pro-viral microRNA that suppresses type-I interferon signaling to promote H1N1 and NDV replication.

The paper develops a method to collect hippocampal interstitial fluid extracellular vesicles (EVISF) and finds sex-dependent changes in microglial EV proteome related to Aβ pathology.

This study shows that separase and caspases, though specialized in cell division and apoptosis, can partially substitute for each other in C. elegans, suggesting evolutionary co-option of cellular components.