Heike Bickeböller

Large-scale association study identifies lung cancer susceptibility copy number variants and their potential functional role in genetic instability

The paper identifies lung cancer susceptibility copy number variants (CNVs) and shows their potential role in genomic instability through association analyses and functional validation.

ImputAccur: fast and user-friendly calculation of genotype-imputation accuracy-measures

ImputAccur calculates genotype-imputation accuracy measures like info, Iam-hiQ, and r² from imputation software outputs, offering filtering and a user-friendly tool.

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

The paper identifies genetic links between impaired pulmonary function and increased lung cancer risk, showing causal relationships through Mendelian randomization and highlighting immune-related pathways.

Shared heritability and functional enrichment across six solid cancers

This study quantifies genetic correlations between six solid cancers and other diseases using GWAS data, finding shared heritability and functional enrichment in regulatory regions.