Mattias Johansson

The paper identifies lung cancer susceptibility copy number variants (CNVs) and shows their potential role in genomic instability through association analyses and functional validation.

This study identifies 40 circulating proteins associated with cancer risk using MR and colocalization, highlighting potential therapeutic targets and adverse effects of protein-altering interventions.

This study identifies eight novel lung cancer susceptibility loci and shows that germline variants related to smoking and DNA repair influence somatic mutation burden in lung tumors.

The paper introduces a pipeline to normalize and pool metabolomics data across studies, improving comparability and reducing inter-study variability.

This study identifies IL-18 as a biomarker for reduced lung cancer risk using genetic, pre-diagnostic, and tumor expression data, with potential therapeutic implications.

This study integrates polygenic risk scores with modifiable risk factors and family history to improve cancer risk prediction across 16 cancers using UK Biobank data.

The paper identifies genetic links between impaired pulmonary function and increased lung cancer risk, showing causal relationships through Mendelian randomization and highlighting immune-related pathways.