Characterization of proteome-size scaling by integrative omics reveals mechanisms of proliferation control in cancer
Ian Jones, Lucas Dent, Tomoaki Higo, Theodoros I. Roumeliotis, Mar Arias-García, Hansa Shree, Jyoti Sharma Choudhary, Malin Pedersen, Chris Bakal
The paper uses multi-omic data to show how protein and mRNA scaling with cell size regulates proliferation in melanoma cells, revealing mechanisms of growth and division coupling.
Science Advances · Jan 25, 2023Peer-reviewedSystems Biology