Author

Ian Jones

Institute of Cancer ResearchORCID 0000-0002-7491-1793Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Chris BakaliD· 2 shared Jyoti Sharma ChoudharyiD· 2 shared Theodoros I. RoumeliotisiD· 2 shared Alan R. LehmanniD· 1 shared Andrea DegasperiiD· 1 shared Cherif BadjaiD· 1 shared Ching Chiek KohiD· 1 shared Christian FrezzaiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Chris BakalORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 22, 2023

A rare genetic disorder provides insights into mechanisms of early-onset neurodegeneration

Cherif Badja, Sophie Momen, Ching Chiek Koh…·Serena Nik‐Zainal

This study investigates neurodegeneration in Xeroderma pigmentosum using stem cell-derived neurons, identifying endoplasmic reticulum stress and UPS dysfunction as key factors and developing an early detection assay.

DOI 10.1101/2023.05.22.23290124

humanbulk RNA-seq

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Systems BiologyScience AdvancesPeer-reviewedJan 25, 2023

Characterization of proteome-size scaling by integrative omics reveals mechanisms of proliferation control in cancer

Ian Jones, Lucas Dent, Tomoaki Higo…·Chris Bakal

The paper uses multi-omic data to show how protein and mRNA scaling with cell size regulates proliferation in melanoma cells, revealing mechanisms of growth and division coupling.

19 citations

humanproteomics

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