Direct inhibitors of InhA with efficacy similar or superior to isoniazid in novel drug regimens for tuberculosis
Lourdes Encinas, Si‐Yang Li, Joaquín Rullás, Rokeya Tasneen, Sandeep K. Tyagi, Heena Soni, Adolfo García-Pérez, Jin Lee, Rubén González del Río, Jaime de Mercado, Verónica Sousa, Izidor Sosič, Stanislav Gobec, Alfonso Mendoza-Losana, Paul J. Converse, , Eric L. Nuermberger
This study evaluates direct inhibitors of InhA (DIIs) for tuberculosis treatment, showing their efficacy comparable to isoniazid and their potential in new drug regimens.
Antimicrobial Agents and Chemotherapy · Sep 30, 2024Peer-reviewedPharmacology & Toxicology