Genome-wide CRISPR screens identify noncanonical translation factor eIF2A as an enhancer of SARS-CoV-2 programmed -1 ribosomal frameshifting
Lian-Huan Wei, Yu Sun, Junjie U. Guo
The paper identifies eIF2A as a host factor that enhances SARS-CoV-2 -1 ribosomal frameshifting through direct RNA interaction.
Cell Reports · Aug 1, 2023Peer-reviewedMolecular Biology