Yu Sun

The paper shows that alternative translation initiation sites produce proteoforms with distinct localization and functions, specifically in synaptic organizers like NPR and C1q-like proteins.

The paper identifies eIF2A as a host factor that enhances SARS-CoV-2 -1 ribosomal frameshifting through direct RNA interaction.

This study identifies merafloxacin as a -1 PRF inhibitor that impedes SARS-CoV-2 replication in vitro.

This study shows that C9orf72 dipeptide repeats inhibit UPF1-mediated RNA decay without requiring stress granule formation, contributing to RNA accumulation in c9ALS/FTD.