Molecular BiologyiSciencePeer-reviewed
Structural insights on the ligand selectivity of the mouse trace amine-associated receptor TAAR7e
Yingjian Liu, Junhong He, Jiahui Sun…·Weihong Liu
This study investigates the molecular mechanisms of ligand selectivity in mTAAR7e using homology modeling, structure-activity analysis, and mutagenesis, revealing structural determinants for preference toward longer carbon chains and tertiary amines.
DOI 10.1016/j.isci.2026.116688