Raymond C. K. Chan

This study uses fMRI to identify shared and distinct neural systems in mental time travel and affective experiences, showing the DMN's role in both and dissociations in valence and temporal processing.

This study conducts a GWAS and cross-ethnic meta-analysis of schizophrenia phenotypes in Hong Kong Chinese and European populations, identifying genetic variants and building predictive models for clinical outcomes.

The paper identifies genetically distinct patient subgroups across diseases by analyzing polygenic risk and pathway convergence.

The paper uses brain cell-type-specific protein interactomes to interpret genetic data in schizophrenia and identifies enriched networks and genes associated with the disease.

A genome-wide association study of 69,369 schizophrenia cases and 236,642 controls identifies 270 risk loci, prioritizes 130 genes, and links common and rare risk variants to neuronal synaptic biology.

This study identifies sex-dependent genetic risk loci shared and specific to mood and psychotic disorders using genome-wide interaction analysis.

The paper compares ten polygenic score methods for psychiatric disorders across multiple cohorts, finding that some methods significantly improve prediction statistics over the baseline PC+T method.

The paper finds a genetic association between schizophrenia risk and age at first birth in women, with different genetic correlations in younger and older age groups.

This study identifies 114 genome-wide significant loci for schizophrenia and bipolar disorder, with specific subphenotype associations and four genes distinguishing the disorders.

This study compares LDSC and GREML methods for estimating genetic correlation, showing GREML provides higher accuracy, especially in the presence of genetic heterogeneity.

The paper examines the heritability of neural activation in the nucleus accumbens during monetary incentive anticipation and its genetic covariance with self-reported pleasure experience in twin pairs.