The ancient cardioprotective mechanisms of ACE2 bestow SARS-CoV-2 with a wide host range
Gianni M. Castiglione, Lingli Zhou, Zhenhua Xu, Zachary M. Neiman, Chien‐Fu Hung, Elia J. Duh
The paper shows SARS-CoV-2 exploits ACE2's catalytic activity to infect a wide range of species through specific mutations that block viral binding.
bioRxiv · Jan 3, 2021 · PreprintMolecular Biology