Structural and functional analysis of pyocin S8 from Pseudomonas aeruginosa : requirement of a glutamate in the H-N-H motif for the DNase activity.
Helena Turano, Fernando Gomes, Renato Mateus Domingos, Maximilia Frazão de Souza Degenhardt, Cristiano L. P. Oliveira, Richard Charles Garratt, Nilton Lincopán, Luís Eduardo Soares Netto
This paper characterizes the structural and functional properties of pyocin S8, showing that a conserved glutamate in the H-N-H motif is essential for its DNase activity and antimicrobial function.
bioRxiv · Apr 29, 2020 · PreprintMolecular Biology