Identification of novel human 15-lipoxygenase-2 (h15-LOX-2) inhibitors using a virtual screening approach
Lucas Gasparello Viviani, Thais Satie Iijima, Erika Piccirillo…·Sayuri Miyamoto
This study identifies six novel h15-LOX-2 inhibitors using virtual screening from a curated ZINC database, with two showing micromolar potency and a mixed-type inhibition mechanism.