Author

Richard Charles Garratt

Universidade de São PauloORCID 0000-0002-2016-3179Unclaimed ORCID profile · follow to get notified of new preprints

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Richard Charles Garratt1 paper

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Assay:protein structure· 1

Frequent Co-Authors

Ana Paula Ulian de AraújoiD· 2 shared Alejandra VelasqueziD· 1 shared Andressa Patrícia Alves PintoiD· 1 shared Cristiano L. P. OliveiraiD· 1 shared Diego A. LeonardoiD· 1 shared Fernando GomesiD· 1 shared Giovanna Christe dos Reis SaladinoiD· 1 shared H.M. PereiraiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMolecular Biology

Ana Paula Ulian de AraújoORCID

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3 papers

Recent·Most cited

Coiled-coil homo-oligomerization and disaggregase Hsp104 act in parallel to stabilize orphan septins

Ítalo A. Cavini, Randi Yeager, Alejandra Velasquez, Andressa Patrícia Alves Pinto, Ana Paula U Araujo, Richard Charles Garratt, Michael A. McMurray

The paper shows that orphan septins form coiled-coil homomers and are stabilized by Hsp104 to prevent degradation and maintain subunit stoichiometry.

bioRxiv · Oct 3, 2026 · PreprintMolecular Biology

A Key Piece of the Puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and Its Implications for Self-Assembly

Rafael Marques da Silva, Giovanna Christe dos Reis Saladino, Diego A. Leonardo, H.M. Pereira, Susana Andréa Sculaccio, Ana Paula Ulian de Araújo, Richard Charles Garratt

The paper presents the first crystal structure of a yeast septin heterodimer, providing insights into the structural biology of yeast septins and their interfaces.

bioRxiv · Apr 22, 2023 · PreprintMolecular Biology

Structural and functional analysis of pyocin S8 from Pseudomonas aeruginosa : requirement of a glutamate in the H-N-H motif for the DNase activity.

Helena Turano, Fernando Gomes, Renato Mateus Domingos, Maximilia Frazão de Souza Degenhardt, Cristiano L. P. Oliveira, Richard Charles Garratt, Nilton Lincopán, Luís Eduardo Soares Netto

This paper characterizes the structural and functional properties of pyocin S8, showing that a conserved glutamate in the H-N-H motif is essential for its DNase activity and antimicrobial function.

bioRxiv · Apr 29, 2020 · PreprintMolecular Biology