Author

Arijit Sarkar

HUN-REN Szegedi Biológiai KutatóközpontORCID 0000-0002-3447-1295Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:simulation· 1

Frequent Co-Authors

Argha MitraiD· 2 shared Attila BoricsiD· 2 shared Krisztina BuzásiD· 1 shared Mária HarmatiiD· 1 shared Márton Richárd SzabóiD· 1 shared Szabolcs DvorácskóiD· 1 shared Zoltán LipinszkiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Argha MitraORCID

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2 papers

Recent·Most cited

Molecular BiologyComputational and Structural Biotechnology JournalPeer-reviewedJan 1, 2025

Evidencing the role of a conserved polar signaling channel in the activation mechanism of the u-opioid receptor

Arijit Sarkar, Szabolcs Dvorácskó, Zoltán Lipinszki…·Attila Borics

The paper investigates the role of a conserved polar signaling channel in the activation of the mu-opioid receptor through mutations and simulations, showing its critical role in agonist binding and G protein stimulation.

1 citation

humanstatistical model

𝕏 PostBluesky

Molecular BiologyBiomoleculesPeer-reviewedApr 30, 2021

Correlated motions of conserved polar motifs lay out a plausible mechanism of G protein-coupled receptor activation.

Argha Mitra, Arijit Sarkar, Márton Richárd Szabó, Attila Borics

The paper uses molecular dynamics simulations to propose a mechanism for GPCR activation involving correlated motions of conserved polar motifs.

6 citations

protein structurestatistical model

𝕏 PostBluesky