Author

Attila Borics

HUN-REN Szegedi Biológiai KutatóközpontORCID 0000-0002-6331-3536Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:simulation· 1

Frequent Co-Authors

Argha MitraiD· 3 shared Arijit SarkariD· 2 shared Annelies JanssensiD· 1 shared Bahar BazeliiD· 1 shared Balázs István TóthiD· 1 shared Balázs KelemeniD· 1 shared Erika LisztesiD· 1 shared Katalin E. KövériD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Argha MitraORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants

Balázs István Tóth, Bahar Bazeli, Annelies Janssens, Erika Lisztes, Márk Racskó, Balázs Kelemen, Mihály Herczeg, Tamás Milán Nagy, Katalin E. Kövér, Argha Mitra, Attila Borics, Tamás Bı́ró, Thomas Voets

This study shows rapamycin directly activates TRPM8 ion channels by binding to a novel site, distinct from known agonists, and highlights implications for drug development and research methods.

eLife · Sep 30, 2025Peer-reviewedNeuroscience

Evidencing the role of a conserved polar signaling channel in the activation mechanism of the u-opioid receptor

Arijit Sarkar, Szabolcs Dvorácskó, Zoltán Lipinszki, Argha Mitra, Mária Harmati, Krisztina Buzás, Attila Borics

The paper investigates the role of a conserved polar signaling channel in the activation of the mu-opioid receptor through mutations and simulations, showing its critical role in agonist binding and G protein stimulation.

Computational and Structural Biotechnology Journal · Jan 1, 2025Peer-reviewedMolecular Biology

Correlated motions of conserved polar motifs lay out a plausible mechanism of G protein-coupled receptor activation.

Argha Mitra, Arijit Sarkar, Márton Richárd Szabó, Attila Borics

The paper uses molecular dynamics simulations to propose a mechanism for GPCR activation involving correlated motions of conserved polar motifs.

Biomolecules · Apr 30, 2021Peer-reviewedMolecular Biology