Multipotent tail bud cells originated with the chordate common ancestor
Tasuku Ishida, Wei-Chen Chu, Jr‐Kai Yu, Yutaka Satou
The paper traces the fate of tail bud cells in amphioxus, showing they generate neural tube, notochord, and somites, supporting the hypothesis that ancestral chordates had multipotent tail bud cells.
bioRxiv · Oct 28, 2026 · PreprintDevelopmental Biology