Po-Yen Lin

Dodecagon light-sheet fluorescence microscopy for large-volume imaging without striping artifacts

This paper introduces dodecagon light-sheet fluorescence microscopy (dodecaLSFM) to eliminate striping artifacts in large-volume imaging, demonstrating its effectiveness in imaging whole mouse brain vasculature and combining with expansion microscopy for 3D cellular resolution.

Plasma membrane mediated GLUT10 mitochondrial targeting regulates intracellular ascorbic acid homeostasis

The paper identifies a novel role of GLUT10 in maintaining intracellular ascorbic acid homeostasis through a noncanonical trafficking pathway involving the plasma membrane and endosomes.

Chromatin Fiber Folding Represses Transcription and Loop Extrusion in Quiescent Cells

The paper shows that chromatin fiber folding in quiescent yeast represses transcription and loop extrusion, with H4 tail modifications affecting fiber structure and function.