Molecular BiologyMolecular MetabolismPeer-reviewed
Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure
Jason Fan, Wen Juan Du, Ja Young Kim-Muller…·Domenico Accili
This study identifies Cyb5r3 as a mediator of FoxO1-dependent mitochondrial dysfunction in beta-cells, leading to impaired insulin secretion and glucose intolerance.
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