Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
An integrative transcriptional logic model of hepatic insulin resistance
Takumi Kitamoto, Taiyi Kuo, Atsushi Okabe…·Domenico Accili
This paper investigates the transcriptional regulation of lipid and glucose metabolic genes in hepatic insulin resistance, finding distinct regulatory patterns and a model for their coexistence in type 2 diabetes.
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