Author

Wen Juan Du

Columbia University Irving Medical CenterORCID 0000-0002-8138-774XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Domenico AcciliiD· 2 shared Jason FaniD· 2 shared Takumi KitamotoiD· 2 shared Bryan DiaziD· 1 shared Christian GarciaiD· 1 shared Delfina LarreaiD· 1 shared Edward Owusu-AnsahiD· 1 shared Hitoshi WatanabeiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersDevelopmental Biology

Domenico AcciliORCID

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2 papers

Recent·Most cited

Developmental BiologyMolecular MetabolismPeer-reviewedOct 28, 2022

Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes

Takumi Kitamoto, Yun‐Kyoung Lee, Nishat Sultana…·Domenico Accili

The paper shows that a small molecule FoxO1 inhibitor generates gut β-like cells, improving glucose tolerance in diabetes models.

12 citations

mouseexperimental assay

𝕏 PostBluesky

Molecular BiologyMolecular MetabolismPeer-reviewedFeb 4, 2020

Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure

Jason Fan, Wen Juan Du, Ja Young Kim-Muller…·Domenico Accili

This study identifies Cyb5r3 as a mediator of FoxO1-dependent mitochondrial dysfunction in beta-cells, leading to impaired insulin secretion and glucose intolerance.

45 citationstop 3%

mouseexperimental assay

𝕏 PostBluesky