Rpd3L Coordinates Chromatin State and Transcription-Replication Conflict Resolution through H3K4 Methylation-Dependent and Independent Mechanisms
Shin Yen Chong, Yaling Chen, Yueh-Tzu Hsu, Chia-Ling Hsu, Tsai-Ming Lu, Yi‐Chen Lo, Cheng-Fu Kao
This study shows Rpd3L modulates chromatin state and resolves transcription-replication conflicts in yeast through H3K4 methylation-dependent and independent mechanisms, preventing genome instability.
bioRxiv · Apr 15, 2026 · PreprintMolecular Biology