Author

Douaa Mugahid

Harvard UniversityORCID 0000-0002-3455-2992Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:non-human primate· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Douglas A. LauffenburgeriD· 2 shared JoAnne L. FlynniD· 2 shared Pauline A MaielloiD· 2 shared Philana Ling LiniD· 2 shared Sarah M. FortuneiD· 2 shared Alex K. ShalekiD· 1 shared Amy J. MyersiD· 1 shared Beth A. Fallert Junecko· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersSystems Biology

Douglas A. LauffenburgerORCID

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2 papers

Recent·Most cited

Markov Field network integration of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques

Shu Wang, Amy J. Myers, Edward B. Irvine, Chuangqi Wang, Pauline A Maiello, Mark Rodgers, Jaime A. Tomko, Kara B. Kracinovsky, Henry Jacob Borish, Michael C. Chao, Douaa Mugahid, Patricia A. Darrah, Robert A. Seder, Mario Roederer, Charles A. Scanga, , Douglas A. Lauffenburger

The paper uses Markov Fields to integrate multi-modal immune data from vaccinated macaques, identifying critical immune interactions and predicting perturbation effects.

Cell Systems · Nov 5, 2024Peer-reviewedSystems Biology

Systematic deconstruction of myeloid cell signaling in tuberculosis granulomas reveals IFN-γ, TGF-β, and time are associated with conserved myeloid diversity

Joshua M. Peters, Hannah Priyadarshini Gideon, Travis K. Hughes, Cal Gunnarsson, Pauline A Maiello, Douaa Mugahid, Sarah K. Nyquist, Joshua D. Bromley, Paul C. Blainey, Beth A. Fallert Junecko, Molly L. Nelson, Douglas A. Lauffenburger, Philana Ling Lin, JoAnne L. Flynn, Alex K. Shalek, , Bryan D. Bryson

This study uses multi-omics approaches to analyze myeloid cell diversity in TB granulomas and identifies IFN-γ, TGF-β, and time as factors driving macrophage diversity.

bioRxiv · May 24, 2024 · PreprintImmunology