Author

Hélène Quach

Centre National de la Recherche ScientifiqueORCID 0000-0002-3493-0973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Lluís Quintana‐MurciiD· 3 shared Maxime RotivaliD· 3 shared Julien Pothlichet· 2 shared Nora Zidane· 2 shared Aurélie BisiauxiD· 1 shared Aurélie CobatiD· 1 shared Daniela MatuozzoiD· 1 shared Étienne PatiniD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersGenomics

Lluís Quintana‐MurciORCID

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3 papers

Recent·Most cited

GenomicsFrontiers in ImmunologyPeer-reviewedNov 29, 2021

Heterogeneity of monocyte subsets and susceptibility to influenza virus contribute to inter-population variability of protective immunity

Mary B. O’Neill, Hélène Quach, Julien Pothlichet…·Lluís Quintana‐Murci

The paper investigates monocyte subset heterogeneity and its impact on influenza virus susceptibility across populations, revealing differences in transcriptional responses and infection resistance between African and European ancestry individuals.

27 citations

humanscRNA-seq

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GenomicsGenome biologyPeer-reviewedJul 30, 2020

Population variation of miRNAs and isomiRs and their impact on human immunity to infection

Maxime Rotival, Katherine J. Siddle, Martin Silvert…·Lluís Quintana‐Murci

The paper analyzes miRNA and isomiR variation in human monocytes across populations and infection, finding population differences driven by non-genetic factors and limited genetic control.

30 citations

humanDNA methylation

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GenomicsGenome biologyPeer-reviewedDec 1, 2018

Exploring the Genetic Basis of Human Population Differences in DNA Methylation and their Causal Impact on Immune Gene Regulation

Lucas T. Husquin, Maxime Rotival, Maud Fagny…·Lluís Quintana‐Murci

The paper identifies ancestry-related DNA methylation differences and their causal impact on immune gene regulation using monocytes and Bayesian analysis.

149 citationstop 3%

humanDNA methylation

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