Author
Centre National de la Recherche ScientifiqueORCID 0000-0003-2519-8044Unclaimed ORCID profile · follow to get notified of new preprints
11 papers
Recent·Most cited
Zhi Li, Gaspard Kerner, Javier Mendoza‐Revilla…·Maxime Rotival
The paper identifies regulatory effects of Neanderthal and Denisovan introgression in immune-related genes using a massively parallel reporter assay across different cell types.
Aurélien Boyance, Nelly Gilles, Maxime Rotival…·Yoann Rombouts
This study identifies ST8SIA4-mediated polysialylation as essential for CCR2-driven monocyte egress from the bone marrow, revealing a novel regulatory mechanism in immune cell trafficking.
Mengliang Ye, Maxime Rotival, Sebastián Amigorena, Elina Zueva
The paper traces the evolutionary impact of transposons on human inflammatory enhancers and shows their role in disease susceptibility through population genetics analysis.
Michaela Zwyer, Zhi Ming Xu, Amanda J Ross…·Daniela Brites
This study examines the relationship between human genetic ancestry, Mycobacterium tuberculosis diversity, and TB disease severity in Dar es Salaam, Tanzania, finding no significant genetic influence on disease severity.
Yann Aquino, Aurélie Bisiaux, Zhi Li…·Lluís Quintana‐Murci
The paper identifies environmental and genetic factors influencing population differences in SARS-CoV-2 immune responses using single-cell RNA-sequencing data.
Jacob Bergstedt, Sadoune Ait Kaci Azzou, Kristin Tsuo…·Christophe Zimmer
This study identifies factors influencing DNA methylation variation in human blood, showing that cytomegalovirus infection and aging drive methylation changes, with cellular composition and DNA sequence as key predictors.
Barthélémy Caron, Étienne Patin, Maxime Rotival…·Christophe Zimmer
The paper identifies novel genetic and non-genetic factors associated with plasma protein levels in healthy donors, highlighting their impact on immune response variability.
Mary B. O’Neill, Hélène Quach, Julien Pothlichet…·Lluís Quintana‐Murci
The paper investigates monocyte subset heterogeneity and its impact on influenza virus susceptibility across populations, revealing differences in transcriptional responses and infection resistance between African and European ancestry individuals.
Maxime Rotival, Katherine J. Siddle, Martin Silvert…·Lluís Quintana‐Murci
The paper analyzes miRNA and isomiR variation in human monocytes across populations and infection, finding population differences driven by non-genetic factors and limited genetic control.
Lucas T. Husquin, Maxime Rotival, Maud Fagny…·Lluís Quintana‐Murci
The paper identifies ancestry-related DNA methylation differences and their causal impact on immune gene regulation using monocytes and Bayesian analysis.
Kirsten R. McEwen, Sarah Linnett, Harry G. Leitch…·Petra Hájková
This study shows that 2i conditions increase transcriptional heterogeneity in pluripotent stem cells, driven by signaling pathways and negative feedback loss.