Author

Alexander Yang

Yale UniversityORCID 0000-0002-3548-5912Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Christopher N. CrossiD· 1 shared Elizabeth B. PerryiD· 1 shared Jeffrey D. MandelliD· 1 shared Jeffrey Nicholas FiskiD· 1 shared Jeffrey P. TownsendiD· 1 shared José C. CostaiD· 1 shared Julie M. LivingstoneiD· 1 shared Kira A. GlasmacheriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Christopher N. CrossORCID

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1 paper

Recent·Most cited

Somatic evolution of prostate cancer: mutation, selection, and epistasis across disease stages

Moein Rajaei, Alexander Yang, Kira A. Glasmacher, Christopher N. Cross, Jeffrey Nicholas Fisk, Elizabeth B. Perry, Jeffrey D. Mandell, Stephen G. Gaffney, Takafumi N. Yamaguchi, Julie M. Livingstone, José C. Costa, Peter A. Humphrey, Vincent L. Cannataro, Paul Christopher Boutros, Jeffrey P. Townsend

This study quantifies mutation rates, selection coefficients, and epistatic interactions across prostate cancer stages, revealing dynamic selective pressures and therapeutic implications.

bioRxiv · Sep 25, 2025 · PreprintCancer Biology