Author

Stephen G. Gaffney

Yale UniversityORCID 0000-0002-5490-2945Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Alexander YangiD· 1 shared Christopher N. CrossiD· 1 shared Elizabeth B. PerryiD· 1 shared Jeffrey D. MandelliD· 1 shared Jeffrey Nicholas FiskiD· 1 shared Jeffrey P. TownsendiD· 1 shared José C. CostaiD· 1 shared Julie M. LivingstoneiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander YangORCID

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1 paper

Recent·Most cited

Somatic evolution of prostate cancer: mutation, selection, and epistasis across disease stages

Moein Rajaei, Alexander Yang, Kira A. Glasmacher, Christopher N. Cross, Jeffrey Nicholas Fisk, Elizabeth B. Perry, Jeffrey D. Mandell, Stephen G. Gaffney, Takafumi N. Yamaguchi, Julie M. Livingstone, José C. Costa, Peter A. Humphrey, Vincent L. Cannataro, Paul Christopher Boutros, Jeffrey P. Townsend

This study quantifies mutation rates, selection coefficients, and epistatic interactions across prostate cancer stages, revealing dynamic selective pressures and therapeutic implications.

bioRxiv · Sep 25, 2025 · PreprintCancer Biology