BiochemistryThe Journal of Physical Chemistry BPeer-reviewed
Thermodynamic Parameter Estimation for Modified Oligonucleotides Using Molecular Dynamics Simulations
Soon Woo Park, Junehawk Lee, Jung Woo Park…·Sangjae Seo
This study estimates thermodynamic parameters for RNA/DNA hybrid duplexes using MD simulations, finding MMGBSA provides more accurate predictions than MMPBSA for modified oligonucleotides.