Katharina Maisel

Extracellular matrix proteins modulate lymphatic endothelial cell junction morphology and barrier function.

This study investigates how four ECM proteins affect lymphatic endothelial cell barrier function and junction morphology using an in vitro platform, finding fibrin and collagen I enhance barrier integrity.

Development of a Novel Methyl Cellulose Hydrogel with Physiologically-Relevant Controlled Ethanol Release for Cervical Dysplasia Ablation

This paper develops a low-cost methyl cellulose-based ethanol gel for topical treatment of low-grade cervical dysplasia, showing efficacy in vitro and stability under various storage conditions.

Synthetic Mucus Biomaterials Enable Localized Therapeutic Antibody Delivery in Inflammatory Bowel Disease

This study develops synthetic mucin-based hydrogels for localized delivery of anti-TNF- antibodies in IBD, showing improved retention and reduced systemic exposure.

Nanoparticles reveal permanent and reversible changes to lymph node biomechanics during inflammatory response

This study uses nanoparticle tracking to analyze biomechanical changes in lymph nodes during acute inflammation and resolution, revealing sex-dependent differences in ECM remodeling.

Fibroblasts dynamically regulate lymphatic barrier function by modulating cell-cell junctions

This study shows fibroblasts regulate lymphatic barrier function by modulating junctions and cytoskeletal structure, with tissue-specific effects on endothelial behavior.