Raghuvir Singh Tomar

Lipid droplet-sphingolipid crosstalk regulates Doa1 activity and DNA damage response

This study shows that lipid droplets regulate DNA damage response by modulating Doa1 activity, linking lipid metabolism to genome stability and cellular aging.

Metabolic regulation of copper homeostasis governs the Sec61-dependent protein translocation process in Saccharomyces cerevisiae

This study shows that metabolic pathways regulate copper homeostasis and protein translocation in yeast, with amino acids and mitochondrial function playing key roles.

Screening of histone mutants reveals a domain within the N-terminal tail of histone H3 that regulates the Tup1-independent repressive role of Cyc8 at the active FLO1

The paper identifies a domain in histone H3's N-terminal tail that regulates Cyc8's repressive role at the FLO1 promoter, independent of Tup1, through Hda1-mediated mechanisms.

Cdc73 majorly regulates apoptosis-inducing factor (AIF1) in Saccharomyces cerevisiae via the H3K36 methylation

The paper shows that Cdc73 regulates AIF1 expression in yeast under hydrogen peroxide stress through H3K36 methylation, independent of H3K4 methylation.

The SWI/SNF and RSC Cooperatively Remodel the Promoters of Unfolded Protein Response Targets and Heat Shock Genes

This study shows that SWI/SNF and RSC chromatin remodelers cooperate to remodel promoters of UPR, HSP, and PQC genes during unfolded protein stress, with SWI/SNF recruitment dependent on Hac1 and other factors.

A novel link between Cell Wall Integrity pathway and Flocculation, regulated by yeast Sen1 dependent interplay between Rlm1 and Tup1

The paper identifies a molecular link between the Cell Wall Integrity (CWI) pathway and flocculation in yeast, regulated by Sen1-mediated interaction between Rlm1 and Tup1.