Brenda B. Diergaarde

This study conducts a cross-ancestral GWAS and fine mapping of head and neck squamous cell carcinoma subsites, identifying 29 novel variants and highlighting gene-environment interactions.

The paper estimates HHT prevalence using gnomAD variant frequencies and three methods, finding it 2-12 times higher than current estimates.

UNSEG provides an unsupervised method for segmenting cells and their nuclei in complex tissue samples without training data, outperforming deep learning methods in generalization and consistency.

This study uses Mendelian randomization to assess the causal effect of sexual behavior on oropharyngeal cancer risk, finding attenuated associations after adjusting for confounders.

This study identifies 13 new genetic loci specific to proximal or distal colorectal cancer subtypes, revealing partly distinct genetic architectures for these tumor locations.

The paper identifies microRNAs whose target sites are modified by global APA events in breast cancer, showing their role in tumor progression and patient-specific heterogeneity.