Author

Soumen Basak

National Institute of ImmunologyORCID 0000-0002-3586-1279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Yashika RatraiD· 2 shared Abhyudai SinghiD· 1 shared Amit SinghiD· 1 shared Bhawna· 1 shared Budhaditya ChatterjeeiD· 1 shared James GomesiD· 1 shared Kasturi GangulyiD· 1 shared Manidipa BanerjeeiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Yashika RatraORCID

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3 papers

Recent·Most cited

A dominant role of cell death in limiting Chandipura virus propagation at cell-saturating high multiplicity of infection

Bhawna, Swapnava Basu, Syed Yusuf Mian, Sanchi Arora, Yashika Ratra, Kasturi Ganguly, Sachendra S. Bais, Manidipa Banerjee, Abhyudai Singh, Soumen Basak

The paper shows that cell death, not type-1 interferons, limits Chandipura virus propagation at high multiplicity of infection.

mBio · Jun 15, 2026Peer-reviewedSystems Biology

Modeling the Co-Activation of Inflammatory Genes1Mediated by NFκB and IRF-3 During Viral Infections

Syona Tiwari, Soumen Basak, R. Pandey

The paper develops a mathematical model to show how NFκB and IRF-3 co-regulate IFNβ expression during viral infections, with NFκB driving immediate response and IRF-3 causing delayed but persistent expression.

bioRxiv · May 13, 2025 · PreprintSystems Biology

Immune differentiation regulator p100 tunes NF-κB responses to TNF

Budhaditya Chatterjee, Payel Roy, Uday Aditya Sarkar, Mingming Zhao, Yashika Ratra, Amit Singh, Meenakshi Chawla, Supriyo De, James Gomes, Ranjan Sen, Soumen Basak

The paper reveals that p100 modulates NF-κB responses to TNF by enabling a late RelB:p50 activity that alters gene expression programs.

Frontiers in Immunology · May 7, 2019Peer-reviewedSystems Biology