Human genetic variation shapes the antibody repertoire across B cell development
Oscar L. Rodriguez, Xiang Qiu, Kaitlyn M. Shields, Christopher Dunn, Amit Singh, Mary Kaileh, Corey T. Watson, Ranjan Sen
The paper investigates how genetic variation and selection shape antibody repertoires across B cell development stages, finding distinct roles for genetics and selection in heavy and light chain repertoires.
bioRxiv · May 19, 2025 · PreprintGenomics