Kee-Myoung Nam

This study characterizes the physical properties and conformational dynamics of Vibrio cholerae exopolysaccharides to understand their role in biofilm matrix mechanics.

The paper investigates mechanisms for output decoupling in molecular systems where steady-state levels change with input concentration while activation times remain constant.

The paper uses single-cell imaging to show phenotypic sorting and bet-hedging in Vibrio cholerae biofilms through c-di-GMP level differences.

This study identifies RbmB as a polysaccharide lyase that cleaves Vibrio cholerae VPS, contributing to biofilm dispersal and suggesting its potential as an antibacterial enzyme.

The paper derives a mathematical model explaining the ABC Score formula for enhancer-gene prediction and shows its limitations in capturing non-additive effects.

The paper shows that Hill functions are the universal limit for sharpness of input-output responses in thermodynamic equilibrium models.

The paper examines how the 3D genome landscape and disease influence the functional associations of human genes based on their evolutionary age and lineage restriction.

The paper analyzes parameter geography in PTM systems to assess robustness, finding that bistability is rare under realistic enzyme mechanisms.