Author

Jelena Erceg

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 3 Genomics· 3 Developmental Biology· 2 Bioinformatics· 1

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Approach:statistical model· 6 Research Focus:gene regulatory network inference· 5 Assay:Hi-C· 5 Approach:experimental assay· 4 Organism:human· 4 Organism:Drosophila· 3 Organism:mouse· 3 Research Focus:spatial domain detection· 3

Frequent Co-Authors

Chao-ting WuiD· 6 shared Ruth B. McColeiD· 5 shared Wren SayloriD· 4 shared Jumana AlHaj AbediD· 3 shared Son C. NguyeniD· 3 shared Anton A. GoloborodkoiD· 2 shared Brian J. BeliveauiD· 2 shared Bryan R. LajoieiD· 2 shared

Activity by Year

2017-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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6 shared papersGenetics

Chao-ting WuORCID

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Author profile →

9 papers

Recent·Most cited

Developmental expression of the skeletal muscle determination gene, MyoD, is regulated by novel enhancer elements that interact with the core enhancer and distal regulatory region

Heather K Jamieson, James R. Camp, Katherine Fleck, Cory J Jubinville, Erica Korolev, Jennifer Cj Chen, Leighton J. Core, Jelena Erceg, Masakazu Yamamoto, David J. Goldhamer

The paper identifies novel enhancer elements that regulate MyoD expression during skeletal muscle development and show they are part of a cis-regulatory network.

bioRxiv · Jul 30, 2026 · PreprintDevelopmental Biology

The functional organization of chromosome territories in single nuclei during zygotic genome activation

Akshada Shankar Ganesh, Taylor M. Orban, Romir Raj, Peter I. Fatzinger, Anna Johnson, Sean M. Riccard, Akhmed Zhanaidarov, Mayu Inaba, Jelena Erceg

This study uses high-resolution imaging to examine chromosome territory organization during zygotic genome activation, revealing large-scale homolog pairing and transcriptional dynamics in single nuclei.

Scientific Reports · Jan 18, 2026Peer-reviewedDevelopmental Biology

Disentangling spatial organization and splicing of rare intron classes in the human genome

Saren M. Springer, Katherine Fleck, Kaitlin N. Girardini, Sean M. Riccard, Jelena Erceg, Rahul Kanadia

The paper investigates how spatial organization and splicing of rare intron classes are related in human cells, finding that intron identity, not position, primarily determines splicing efficiency.

bioRxiv · Aug 11, 2025 · PreprintBioinformatics

The genome-wide, multi-layered architecture of chromosome pairing in early Drosophila embryos

Jelena Erceg, Jumana AlHaj Abed, Anton A. Goloborodko, Bryan R. Lajoie, Geoffrey Fudenberg, Nezar A. Abdennur, Maxim Imakaev, Ruth B. McCole, Son C. Nguyen, Wren Saylor, Eric F. Joyce, Tharanga Niroshini Senaratne, Mohammed A. Hannan, Guy Nir, Job Dekker, , Chao-ting Wu

A haplotype-resolved Hi-C approach reveals structured homolog pairing in early Drosophila embryos, correlated with Zelda-mediated chromatin accessibility.

Nature Communications · Oct 3, 2019Peer-reviewedGenetics

Highly Structured Homolog Pairing Reflects Functional Organization of the Drosophila Genome

Jumana AlHaj Abed, Jelena Erceg, Anton A. Goloborodko, Son C. Nguyen, Ruth B. McCole, Wren Saylor, Geoffrey Fudenberg, Bryan R. Lajoie, Job Dekker, Leonid A. Mirny, Chao-ting Wu

The paper uses haplotype-resolved Hi-C to reveal structured homolog pairing and its global impact on gene activity in hybrid Drosophila cells.

Nature Communications · Oct 3, 2019Peer-reviewedGenetics

Islands of retroelements are the major components of Drosophila centromeres

Ching-Ho Chang, Ankita Chavan, Jason Palladino, Xiaolu Wei, Nuno M. C. Martins, Bryce Santinello, Chin-Chi Chen, Jelena Erceg, Brian J. Beliveau, Chao-ting Wu, Amanda M. Larracuente, Barbara G. Mellone

The paper identifies the sequence composition of Drosophila melanogaster centromeres, showing they are composed of retroelement islands flanked by satellite repeats, with G2/Jockey-3 being the most enriched retroelement.

PLoS Biology · May 14, 2019Peer-reviewedGenomics

Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling

Guy Nir, Irene Farabella, Cynthia Pérez Estrada, Carl G. Ebeling, Brian J. Beliveau, Hiroshi M. Sasaki, S. Dean Lee, Son C. Nguyen, Ruth B. McCole, Shyamtanu Chattoraj, Jelena Erceg, Jumana AlHaj Abed, Nuno M. C. Martins, Huy Q. Nguyen, Mohammed A. Hannan, , Chao-ting Wu

The paper uses super-resolution imaging and integrative modeling to achieve 10 kb resolution of chromosome folding.

PLoS Genetics · Dec 26, 2018Peer-reviewedGenetics

Ultraconserved elements occupy specific arenas of three-dimensional mammalian genome organization

Ruth B. McCole, Jelena Erceg, Wren Saylor, Chao-ting Wu

This study examines the relationship between ultraconserved elements and three-dimensional genome organization in human and mouse genomes, finding UCEs enriched in contact domains and linked to specific biological processes.

Cell Reports · Jul 1, 2018Peer-reviewedGenomics

Structural disruption of genomic regions containing ultraconserved elements is associated with neurodevelopmental phenotypes

Ruth B. McCole, Wren Saylor, Claire E. Redin, Chamith Y. Fonseka, Harrison Brand, Jelena Erceg, Michael E. Talkowski, Chao-ting Wu

The paper identifies a link between structural genomic disruptions near ultraconserved elements and neurodevelopmental phenotypes.

bioRxiv · Dec 13, 2017 · PreprintGenomics